2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Eukaryotic Initiation Factor (eIF)
  5. Eukaryotic Initiation Factor (eIF) Antagonist

Eukaryotic Initiation Factor (eIF) Antagonist

Eukaryotic Initiation Factor (eIF) Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-12495A
    ISRIB
    		Antagonist 98.58%
    ISRIB is a brain-penetrant inhibitor of integrated stress response (ISR). Persistent activation of the ISR has been linked to the development of several neurological disorders as ISR represses translation through inhibiting eIF2B. ISRIB inhibits the ISR by promoting the nucleotide exchange activity of eIF2B and recovering the translation, and thus can be used for neurological disorders research.